Author(s) :

Soda Abysina Martin, Kasuyi Lufuluabo Jean, Ilombe Gillon, Agasa Batina Salomon , Lutumba Pascal.

Volume/Issue :

Abstract :

Preventing preterm birth, small for gestational age (SGA), and low birth weight (LBW) is critical to the health of children worldwide. Preterm birth, SGA, and LBW are referred to as vulnerable small newborns or VSN. The aim of this study was to determine the survival of VSN born to mothers with iron deficiency anemia or IDA and its predictors. A prospective, matched, open-label, multicenter cohort study of 1,226 newborns of mothers with IDA. We performed statistical analysis, including competing risk analysis and Cox regression modeling, to illustrate the clinical effects of IDA on newborns and risk factors. The risk of clinical effects and the incidence rate of the PT+SGA+LBW phenotype increased by more than 2.21 times (2.20-2.21) and 3.86 times (3.82-3.90), respectively. The risk of the T+SGA+LBW phenotype increased by 1.28 times (1.28-1.29) or 28% for moderate IDA, by 2.48 times (2.47-2.49) for severe IDA. This risk increased by 5.64 times (5.63-5.66) for maternal low birth weight at the end of pregnancy. The risk associated with the PT+AGA+LBW phenotype increased by 1.78 (1.75-1.81) or 78% and by 5.53 (5.47-5.59) times in live births from mothers with low early gestational weight and from mothers without iron supplementation. Maternal iron deficiency anemia has a serious impact on newborn health. Threatened by a higher incidence of mortality and various short- and long-term morbidities, VSNs born to IDA mothers should receive appropriate care.

No. of Downloads :

0